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Programs that offer hormone replacement therapy for transgender individuals who are beginning the anatomical and psychological transition to another sex and gender. The therapy involves taking estrogen (for male-to-female transition) or testosterone (for female-to-male transition) before, during, and after the surgical transition. The purpose of hormone therapy is to change the physical appearance of the individual to look like the other sex and to feel comfortable. The feminizing effects of estrogen and the masculinizing effects of testosterone may appear after the first couple of doses, though it may be several years before a person is satisfactorily transitioned.