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Programs that conduct tests of an individual's genetic material (DNA, RNA, chromosomes, proteins, and certain metabolites) to establish whether there are risk factors associated with particular diseases or disabilities, to help identify or exonerate individuals involved in criminal matters based on DNA evidence, or to establish paternity or maternity for legal or immigration purposes. Genetic testing generally involves individuals suspected of criminal activity or being at high risk for a disease or disability whereas genetic screening is conducted with a broader population about which risk factors are unknown.