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Programs that provide inoculations which prevent contraction of rabies, a viral infection which affects the central nervous system, for individuals whose occupations put them at high risk for exposure (e.g., animal handlers, laboratory workers, forest rangers, taxidermists, veterinarians, animal breeders and hunters) and for individuals who have been exposed to rabies immediately after the exposure occurs. Other individuals whose activities bring them into frequent contact with the rabies virus or potentially rabid bats, raccoons, skunks, cats, dogs or other species at risk of having rabies; and international travelers likely to come in contact with animals in areas of enzootic dog rabies which lack immediate access to appropriate medical care, including biologics, should also be considered for pre-exposure prophylaxis. There is no treatment for rabies once symptoms of the disease appear.