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A condition in which there is a malignancy in the tissue of the breast which is characterized by a lump, thickening or other abnormalities. Included is Paget's disease of the nipple, an uncommon type of cancer that forms in or around the nipple and is characterized mild scaling and flaking which may later spread to the areola or other regions of the breast. The disease may also originate in the areola where it resembles eczema, a non-cancerous, itchy rash. Symptoms may include tingling, itching, increased sensitivity, burning and pain. There may also be discharge from the nipple which may appear flattened against the breast. Most people with Paget's disease of the nipple also have underlying breast cancer which may be invasive or confined to the milk ducts.